Its not the power that kills the drive train but the torque, with a VR6 (lots of torque) I would suggest a maximum of 250/275 bhp
While a lot will depend on you driving style, the more power you have the more likely & more often you will break things, but it should run at 250/275 bhp without breaking to many things to often.
Don’t forget that any & every part of a VR6 drive train is now going to be between 20 & 25 years old, with lots of kilometers clocked up, have you thought about Haldex?